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段金友

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段金友,1974.11生,教授、博士生导师。2012年入选中国科学院‘抗肿瘤药物’交叉创新团队,获得陕西省科学技术二等奖(第二);2013年入选教育部新世纪优秀人才支持计划。
  2003.7获得中国科学院上海药物研究所博士学位;2003.11至2005.2在美国约翰•霍普金斯大学从事糖脂功能博士后研究;2005.2至2010.3在美国哈佛大学医学院从事多糖免疫学博士后研究,于2010.4聘为Instructor in Medicine; 2010.10聘为理学院三级教授。
  目前主持国家基金、省部级项目,主要开展功能性糖组学研究,以第一或通讯作者在细胞子刊Cell host & microbe、国际著名综合性期刊PNAS和Scientific Reports等杂志上发表SCI论文二十余篇。现为第一届中国环境诱变剂学会活性氧生物学效应专业委员会委员,第五届中国生物化学与分子生物学会复合糖专业委员会委员。
研究方向:
1、 内源性两性离子多糖的免疫调节机制
2、多糖新型衍生物的新功能
3、靶向糖尿病和恶性肿瘤的天然活性多糖结构及构效关系
在研项目(主持):
1、国家自然科学基金面上项目(NSFC31270860);
2、高等学校博士学科点专项基金(Z223021302);
3、陕西省科技计划农业攻关项目(2012K02-06);
4、上海中医药大学合作项目(K332021201);
5、高等学校基本科研业务费专项资金科技创新重点项目(Zl09021201);
6、金莎电玩城引进人才专项(Z111021002).
2011年以来学术论文:
1. Haibo Mu, Amin Zhang, Lin Zhang, Hong Niu, Jinyou Duan* Inhibitory effects of chitosan in combination with antibiotics on Listeria monocytogenes biofilm. Food Control, 2014, 38:215-220.
2. Amin Zhang; Haibo Mu; Wuxia Zhang; Guoting Cui; Jie Zhu; Jinyou Duan*. Chitosan coupling makes microbial biofilms susceptible to antibiotics. Scientific Reports. 2013,3:3364.
3.    Vincent L. Chen,Neeraj K. Surana,Jinyou Duan*,Dennis L. Kasper*. Role of murine intestinal interleukin-1 receptor 1-expressing lymphoid tissue inducer-like cells in salmonella infection. PloS One, 2013, 8(6):e65405.
4.    Guodong Wei, Hongwei Wang, Bin Bao, Hongwei Fan, Wuxia Zhang, Jinyou Duan Shunchun Wang*. Homogalacturonans from Preinfused Green Tea: Structural Characterization and Anticomplementary Activity of Their Sulfated Derivatives. Journal of Agricultural and Food Chemistry. 2013, 61(46):10971-80.
5.    Ying Wang, Jianping Fang, Xinyan Ni, Jie Li, Qin Liu, Qun Dong, Jinyou Duan*, and Kan Ding*.Inducement of Cytokine Release by GFPBW2, a Novel Polysaccharide from Fruit Bodies of Grifola frondosa, through Dectin-1 in Macrophages. Journal of Agricultural and Food Chemistry. 2013,61(47):11400-9.
6.    Guoting Cui, Wuxia Zhang, Amin Zhang, Haibo Mu, Hongjin Bai, Jinyou Duan*, Cuiyun Wu*.Variation in antioxidant activities of polysaccharides from Fructus Jujubae in South Xinjiang area.International Journal of Biological Macromolecules, 2013, 57, 278– 284.
7.    Wei Zhou, Chao Huang, Yan Li, Jinyou Duan, Yonghua Wang*, Ling Yang. A systematic identification of multiple toxin-target interactions based on chemical, genomic and toxicological data. Toxicology. 2013, 304:173-84.
8.    Wuxia Zhang, Haibo Mu, Amin Zhang, Guoting Cui, Hua Chen, Jinyou Duan*, Shunchun Wang*. A decrease in moisture absorption-retention capacity of N-deacetylation of hyaluronic acid. Glycoconjugate Journal. 2013, 30(6):577-83.
9.    Haibo Mu, Amin Zhang, Wuxia Zhang, Guoting Cui, Shunchun Wang*, Jinyou Duan*. Antioxidative Properties of Crude Polysaccharides from Inonotus obliquus. International Journal of Molecular Sciences, 2012, 13(7): 9194-9206.
10.    Xue Xu, Wuxia Zhang, Chao Huang, Yan Li, Hua Yu, Yonghua Wang*, Jinyou Duan*, Yang Ling. A Novel Chemometric Method for the Prediction of Human Oral Bioavailability. International Journal of Molecular Sciences, 2012, 13(6): 6964-6982.
11.    Huijun Wang, Hongwei Wang, Songshan Shi, Jinyou Duan, Shunchun Wang*. Structural characterization of a homogalacturonan from Capparis spinosa L. fruits and anti-complement activity of its sulfated derivative. Glycoconjugate Journal. 2012, 29(5-6):379-87.
12.    Jinyou Duan* and Dennis L. Kasper. Regulation of T cells by gut commensal microbiota. Current Opinion in Rheumatology, 2011, 23(4):372-6.
13.    Jinyou Duan* and Dennis L. Kasper*. Oxidative depolymerization of polysaccharides by reactive nitrogen/oxygen species. Glycobiology, 2011, 21(4): 401-409.
2011年前代表性论文:
1.    Jinyou Duan, Hachung Chung, Erin Troy, Dennis L. Kasper*. Microbial colonization drives expansion of IL-1 receptor 1 expressing and IL-17 producing γ/δ T cells. Cell host & microbe, 2010, 7(2): 140-150.
2.    Jinyou Duan. Fikri Y. Avci, Dennis L. Kasper*. Microbial carbohydrate depolymerization by antigen-presenting cells: deamination prior to presentation by the MHCII pathway. PNAS, 2008, 105(13): 5183-8.
联系方式:
陕西杨凌西农路22号, 金莎电玩城理科大楼,邮编 712100
E-mail: jduan@nwsuaf.edu.cn

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